Substance-related disorders are those that involve the misuse of different substances such as cocaine, methamphetamine, opiates, and alcohol.

These disorders may include substance-induced conditions that can result in many associated diagnoses including intoxication, withdrawal, or the emergence of psychosis, anxiety, and delirium. Examples of substance-related disorders include:

• Alcohol-related disorders: These involve the consumption of alcohol, one of the most widely used drugs in the United States.

• Cannabis-related disorders: These disorders include symptoms such as using more marijuana than originally intended, feeling unable to stop it, and continuing to use it despite adverse effects in one's life.

• Inhalant-use disorders: These involve inhaling fumes from things such as paints or solvents. As with other substance-related disorders, people with this condition experience cravings for the substance and find it difficult to control or stop engaging in the behavior.

• Stimulant use disorder: This involves the use of stimulants such as meth, amphetamines, and cocaine.

• Tobacco use disorder: This is characterized by symptoms such as consuming more tobacco than intended, difficulty cutting back or quitting, cravings, and experiencing adverse social consequences as a result of tobacco use.

• Gambling Disorder: The DSM-5 also includes gambling disorder under this classification. The American Psychiatric Association explains that this change "reflects the increasing and consistent evidence that some behaviors, such as gambling, activate the brain reward system with effects similar to those of drugs of abuse and that gambling disorder symptoms resemble substance use disorders to a certain extent."

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